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Thus far, approximately 40 companies worldwide, including Codiak Biosciences, Evox Therapeutics, Tavec Pharmaceuticals, Carmine Therapeutics, Anjarium, and Micromedmark Biotech, have developed exosome-based therapies, which are expected to provide cost-effective and more accurate targeted therapies in the clinic ( However, challenges, such as large-scale production, purity, and batch homogeneity of exosomes, still limit their clinical application
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(Grossulariaceae) leaves (10, 30, and 60 μg/ml) inhibited ICAM-1 expression in TNFα-stimulated LT2 endothelial cells (Garbacki et al., 2005)
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