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When autophagy initiates, LC3-I undergoes a critical modification involving conjugation to phosphatidylethanolamine (PE), converting it to LC3-II, which then localizes to the lipid membrane of nascent autophagosomes (Amaravadi et al., 2011)

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Exercises to Avoid During Acute Flare-Ups The Dangers of Traditional Sit-Ups Traditional sit-ups place excessive pressure on the lower spine