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Higher glutathione improves glutathione‑S‑transferase activity (the pathway that tags toxins for excretion) and helps regenerate vitamins C and E, with measurable changes in 4 to 12 weeks

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Systemic infection is among the serious hazards because live probiotic bacteria (e.g., Lactobacillus or Saccharomyces) may translocate across the gut barrier and induce septicemia, fungemia, or endocarditis