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The mean change in body weight from baseline to week 104 was −15.2% in the semaglutide group ( n = 152) versus −2.6% with placebo ( n = 152), for an estimated treatment difference of −12.6 %-points (95% confidence interval, −15.3 to −9.8

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doi:10.1016/j.phrs.2019.104395 Nathan PJ, Lu K, Gray M, Oliver C