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Joshua Kritzer, an associate professor of chemistry at Tufts University, says the study offers evidence that the stapled peptide approach is worth pursuing and could lead to new drugs that interfere with specific protein interactions

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This may be important since BPC 157 itself not only increased Vegfr2 expression in vascular endothelial cells but also immediately triggered the internalization of Vegfr2 and subsequent phosphorylation of Vegfr2 , Akt, and Nos3 signaling pathways without other known ligands or shear stress (Hsieh et al., 2017)