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EAAT2 regulates synaptic glutamate clearance, is reduced in depression and stress, and represents a potential antidepressant target [182]
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Ion channel modulators, specifically those aimed at PIEZO1 and the Gardos channel, provide a method to restore ionic equilibrium, diminish dehydration, and mitigate hemolysis in conditions like hereditary xerocytosis and sickle cell disease (80)
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![PDF] Safety and Tolerability of the Hexadecapeptide AOD9604 in Humans](https://figures.semanticscholar.org/563e37f40c2395525ecec5ca6cb5d79b0fb753dd/4-Table1-1.png)
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