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Angiogenesis and Wound Healing Models: In rodent excisional wound, burn, and ischemic flap models, co-administration promoted faster wound closure, greater vascularization (upregulated VEGF), increased keratinocyte and fibroblast migration (via TB-500’s actin-binding effects), and superior granulation tissue formation

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[2] McCoy AT, Benoist CC, Wright JW, Kawas LH, Bule-Ghogare JM, Zhu M, Appleyard SM, Wayman GA, Harding JW

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