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To offset potential irritation, the formula also layers in glycerin, sodium hyaluronate, niacinamide, and “a lineup of peptides, plus tetrahexyldecyl ascorbate (a stable vitamin C derivative) for antioxidant defense and an added brightening boost,” says Dr

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However, the order of application matters, some peptide types pair better than others with retinol, and your skin's tolerance determines whether you apply them together or separately