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Although simvastatin reduced Hcy levels in both groups (CC and T carriers), the extent of the decrease in Hcy levels was more pronounced in individuals with the T allele (from 9.4 ± 2.9 to 7.5 ± 1.0 µmol/L) compared to patients with the CC genotype (from 7.6 ± 1.9 to 6.8 ± 1.5 µmol/L)
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There are several neurotrophic agents capable of initiating such beneficial processes including NGF, BDNF, neurotrophin-3 and neurotrophin-4/5 [53-55]
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