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In diet-induced-obese mice (PMID 29155147, 2018), subcutaneous 5-Amino-1MQ at 20 mg/kg three times daily for about eleven days produced roughly 5.1% body-weight loss against continued weight gain in controls, about 35% less epididymal white fat, smaller adipocytes, lower plasma cholesterol and improved glucose tolerance, with no change in food intake

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Eeach other pursuit of improved overall wellness when combined with tirzepatide