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Deeply elucidating molecular anti-aging mechanisms, investigating interactions with other aging-related signaling pathways (such as mTOR, AMPK, etc.), improving the functional network, and providing theoretical support for more efficient anti-aging interventions
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For example, metabolites related to the tricarboxylic acid cycle (e.g., malate, phosphoenolpyruvate) and mitochondrial β-oxidation (propionylcarnitine and butyrylcarnitine) are reduced in rnp-6 mutants, implying mitochondrial dysfunction