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The reported analogs were cytotoxic to OVCAR-3 ovarian cancer cells (in both serum-containing media and serum-free media) and less liable to deactivation by serum proteins compared to free auranofin, possibly due to the protection offered by the micelle system

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Bowel IRI DFO has been shown to prevent lipid peroxidation induced by intestinal I/R and restores reduced GPX4 activity (248)