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Upregulated and downregulated expressions of genes encoding an enzyme with multisubunit have been reported in response to antibiotic stress (Chen et al., accA plays a major role in fatty acid synthesis (Kim, Enhanced biosynthesis of fatty acids is associated with the acquisition of quinolone antibiotic resistance that has been revealed in bacteria, including Vibrio alginolyticus, Edwardsiella tarda , and Xanthomonas oryzae (Cheng et al., P

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Furthermore, Gclc -deficient FoB have a block in the mitochondrial electron transport chain (ETC) due to diminished complex I and II activity and thereby accumulate the tricarboxylic acid cycle metabolite succinate