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In it, the researchers administered MOTS-c to mice at various life stages — young (two months old), middle-aged (12 months old), and old (22 months old) — and saw that subjects at every life stage exhibited improved physical performance in multiple tests, including those assessing motor coordination and running capacity.21 The findings aren’t dissimilar to a 2023 study in humans, which found that a higher serum MOTS-c concentration correlated with “greater muscle mass, force, and power generated during jumping” in healthy subjects.22 Reduced inflammation A 2024 study on mature mice points to MOTS-c’s potential as a treatment for acute and chronic inflammatory disorders
