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We found that TRAF3 overexpression increased the ubiquitination level of ECH1 in HEK293T cells, and we confirmed the result in GBM cells (Figure 3D and Supplemental Figure 3B)

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[9] In contrast, in bacteria , ACC exists as a multienzyme complex composed of three distinct polypeptide chains: biotin carboxylase, carboxyltransferase, and BCCP