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rather, it also extends its influence to mitigating other cell death pathways, such as apoptosis, necroptosis, pyroptosis, and parthanatos [48]

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6 PI3K/Akt signaling pathway Phosphatidylinositol3-kinase/protein kinase B (PI3K/Akt) signaling pathway plays an important role in the recruitment of inflammatory factors and angiogenesis, and is one of the core pathways regulating cell proliferation, metabolism, movement and survival