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2.3 The inflammatory-oxidative axis in MS In MS pathogenesis, the inflammation-driven oxidative burst generated by activated microglia, astrocytes, and infiltrating macrophages play a critical role in demyelination and subsequent injury to neurons, axons, myelin, and oligodendrocytes (Ohl et al., 2016) (Figure 2)
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[PMC free article] [PubMed] [Google Scholar] 90.Selye H
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