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Evidence-based pathogenesis and treatment of ulcerative colitis: A causal role for colonic epithelial hydrogen peroxide

10.1073/pnas.142310499 44 MallisR

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It is therefore possible to state that, depending on the metabolic conditions and/or the cell type, the pyruvate dehydrogenase complex commits carbon intermediates from amino acid and glucose catabolism to: the citric acid cycle, and thus to energy production, for example, in skeletal muscle under aerobic conditions, and always in cardiac muscle