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Astroglial atrophy and loss of function A widespread class of astrocytic changes observed in many neurological diseases and in the majority of neuropsychiatric disorders are represented by structural atrophy and functional asthenia and manifested in the loss of key homoeostatic functions, such as for example glutamate clearance
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Likewise, results obtained in various diet-induced MASLD/MASH rodent models revealed a marked reduction in CAT activity in the serum as well as the liver of these animals as compared to respective controls (Dai et al
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