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Necroptosis plays a dual role in tumour immune regulation, as it can activate antigen-specific immune responses by releasing damage-associated molecular patterns, while RIPK3/MLKL-mediated IL-1α release can suppress T-cell function and promote tumour immune escape [59]

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[DOI] [PubMed] [Google Scholar] 31.Chung JW, Acharya D, Singh JK, Sakong J