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Besides, goiter may be experimentally induced in animals exposed to goitrogenic substances, like perchlorate or thiocyanates, which block iodine uptake in the thyroid gland, causing a similar compensatory rise in secretion of TSH and hyperplasia of thyroid cells (Nourani and Sadr 2023)
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Precipitated withdrawal: Use titration to the minimum effective dose to reverse respiratory depression without provoking severe withdrawal when appropriate (particularly in chronically opioid‑dependent patients)
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