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Synthesized ruthenium(II)-chelates 87a , 87b , and 87c (Figure 89) were found to exhibit a higher cytotoxic potency than Cisplatin towards the following cell lines: human lung carcinoma (A549), Cisplatin-resistant lung carcinoma epithelial cell line (A549/DDP), human liver cancer cell line (HepG2), and human breast cancer cell line (MCF-7)