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Glutathione S-transferase activity in liver, kidney, and spleen. Values... | Download Scientific Diagram

MTs and cardioprotection in diabetes Several studies have demonstrated that MTs can prevent and inhibit cardiac oxidative stress, protecting against the cardiotoxicity caused by chemotherapeutic agents [132], inhibit pathological changes in the hearts of diabetes patients [133], and protect the cardiac endoplasmic reticulum from stress and apoptosis [134, 135]

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The mitochondrial enzyme nicotinamide nucleotide transhydrogenase further modulates redox status by catalyzing the reversible conversion of NADH and NADP+ into NAD+ and NADPH, the latter serving as a crucial factor for GSH reductase-mediated recycling of reduced GSH (92)