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Furthermore, it has been found that the expression of integrin β6 is significantly upregulated in regions of intestinal inflammation, and it plays a crucial role in regulating the intestinal immune environment, macrophage infiltration, and the integrity of the intestinal barrier
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These cardiac repair studies established TB-500 as one of the most extensively characterised peptide research tools for studying cardiac regeneration biology and provided the foundational evidence for thymosin beta-4’s role as an endogenous cardiac repair mediator and establishing that actin-sequestering peptides have biological significance beyond cytoskeletal regulation in the context of cardiac injury response
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