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Mn-dependent superoxide dismutase/superoxide dismutase 2 (MnSOD/SOD2) is an antioxidant mitochondrial metalloenzyme that protects cells from oxidative stress by catalyzing the dismutation of superoxide anion radical to H 2 O 2 and molecular oxygen, regulating cellular redox status and ROS generation (33)

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The following serious adverse reactions are discussed elsewhere in the labeling: Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed cannot be directly compared to rates in other clinical trials and may not reflect the rates observed in practice