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Moreover, chitosan nanoparticles loaded with dsNKG2D-IL-15 fusion gene fragments can also deliver IL-15 and NKG2D genes into cancer cells and bind to NKG2D receptors in NK cells to activate NK cells thereby inducing anti-tumor immune responses and inhibiting tumor growth and ultimately prolonging the survival of tumor-bearing mouse (88)

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L.WangL.et al (2022)