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As in our previous findings, 20 IHC characterization of the AR using the AR 441 monoclonal antibody (supplementary Table 2), which was raised against the aa 299-315 in the N-ter domain of AR and recognizes the full-length AR as well as all C-ter truncated AR variants (ARvs), 20 revealed the LNCaP-AI tumors to be (nuclear) AR +/hi and LAPC9-AI tumors AR -/lo whereas LAPC4-AI and VCaP-AI tumors largely AR cyto (with ~10% AR in the nucleus