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In the face of vitamin B 12 deficiency, conversion of methylmalonyl-CoA to succinyl-CoA cannot take place, which results in accumulation of methylmalonyl-CoA and aberrant fatty acid synthesis
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Sign of toxicity include diarrhoea and generalised body oedema Dosage: The most common dosage is 1000mcg which is 1 ml per treatment every 4-6 weeks This can be given via IM injection in the arm or the bum
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