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Non-muscle myosin IIA was found to localize in all transverse arcs as a punctate pattern, while non-muscle myosin IIB mainly localized to the proximal transverse arcs [33]
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While telomere attrition in humans presumably has evolved as cancer-protective mechanism, individuals born with shorter-than-average telomeres face elevated cancer risk, a phenomenon known as the “telomere paradox”, potentially due to selective expansion of abnormal stem cells and eventual failure of telomere-based tumor suppression (Nassour et al., 2021)
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