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[5] Glutathione depletion has been linked to a number of disease states and groups, including: Athletic overtraining Major injuries and trauma Patients with wasting diseases such as HIV and AIDS Lung cancer Gut-based diseases such as Crohn’s and ulcerative colitis Chronic fatigue syndrome Alcoholism and fatty liver disease Diabetes and low glucose tolerance Cancer [6] Glutathione and autoimmune disease An autoimmune disorder occurs when a person’s immune system mistakenly attacks their own body

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24 However, GSSG is actively excreted from the cell when its intracellular concentration exceeds the reductive capacity of the cell, as in conditions of oxidative stress

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