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To begin with, we will first briefly examine the biochemical principles and highlight the relative importance of the main endogenous pathways of glycine synthesis and degradation

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ALA has also been compared with N -acetylcysteine (NAC) in one study, whereby the authors found that NAC is better than ALA in protecting oxidative kidney injury induced by the chemotherapeutic drug ifosfamide, which is highly toxic to the kidney [173,174,175,176]