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The Mayo Clinic recommends seeing a doctor – or heading to the emergency room – if your headache occurs in the following ways: After a head injury Comes on very quickly like a thunderclap Accompanied by a fever, a stiff neck, seizures, or numbness & weakness in any part of the body – these are symptoms of a stroke If it’s a new headache pain after age 50 Chronic headache pain after coughing, physical activity, straining, or sudden movements Migraines are more common in women than men and seem to have a genetic component