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Circadian pathway Modulation of the circadian rhythm Regulates sleep-wake cycles Normalizes sleep disorders Effects lasting several days Opioid route Endogenous opioid system Pain perception module Blocked by naloxone Supports weaning management Stress response Hypothalamic-pituitary-adrenal axis Reduces stress responses Reduces cortisol secretion Improves stress management Unique biological properties Unlike most peptides, DSIP freely crosses the blood-brain barrier and can be absorbed by the intestine without enzymatic degradation
Lidocaine HCl Injection
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451, 83–88 10.1016/j.neulet.2008.11.058 [DOI] [PubMed] [Google Scholar] Kuhlmann T., Lucchinetti C., Zettl U
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